Personal profile
Research Interests
- Mitochondrial dynamics.
- Exercise physiology.
- Skeletal muscle metabolism.
- Metabolism of energy substrates.
- Circadian clock and its metabolic function in humans.
Personal resume
Mauricio Castro-Sepúlveda is a physical education professor at the University of Playa Ancha. He obtained a Ph.D. in Medical Sciences from the Pontifical Catholic University of Chile. He is a researcher at the Finis Terrae University in Chile, with an initiation FONDECYT project in progress. He is currently also a postdoctoral fellow at the Laboratory of Aging and Muscle Metabolism, led by Francesca Amati, at the University of Lausanne, Switzerland.
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- 1 Similar Profiles
Projects
- 1 Finished
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Fondecyt de Iniciación 2023-Circadian clock in the control of mitochondrial fusion dynamics in human skeletal muscle: potential implications for skeletal muscle quality and metabolic health.
Castro Sepúlveda, M. (PI)
1/01/23 → 1/01/25
Project: Research › Applied research
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Uncovering the muscle clock–mitochondria axis through exercise
Castro-Sepulveda, M., 1 Jan 2026, In: Trends in Endocrinology and Metabolism. 37, 1, p. 4-7 4 p.Research output: Contribution to journal › Short survey
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CCL5 Induces a Sarcopenic-like Phenotype via the CCR5 Receptor
Aguirre, F., Tacchi, F., Valero-Breton, M., Orozco-Aguilar, J., Conejeros-Lillo, S., Bonicioli, J., Iturriaga-Jofré, R., Cabrera, D., Soto, J. A., Castro-Sepúlveda, M., Portal-Rodríguez, M., Elorza, Á. A., Matamoros, A., Simon, F. & Cabello-Verrugio, C., 1 Jan 2025, In: Antioxidants. 14, 1, 84.Research output: Contribution to journal › Article
Open Access1 Scopus citations -
Impact of different exercise modalities on mitophagy in human skeletal muscle
Muñoz-Medina, C., Carriel-Nesvara, A., Botella, J. & Castro-Sepulveda, M., 1 Jan 2025, (Accepted/In press) International Review of Cell and Molecular Biology. Elsevier Inc., (International Review of Cell and Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Mitochondrial dynamics: deciphering the role of HDL-C in regulating mitochondrial function and fatty acid oxidation in human skeletal muscle
Castro-Sepúlveda, M. & Amati, F., 1 May 2025, In: American Journal of Physiology - Heart and Circulatory Physiology. 328, 5, p. H1087-H1088Research output: Contribution to journal › Editorial › peer-review
Open Access -
Pomegranate peel extract counteracts palmitate-induced insulin resistance by inducing mitophagy, reducing inflammation, and regulating MAPK signaling in C2C12 myotubes
Bustamante, A., Gutiérrez, J., Chávez, V., Lemus, R., Muñoz-Medina, C., Carriel-Nesvara, A., León, E., Fredes, C., Aguirre, C., Parada, A., Castro-Sepúlveda, M. & Echeverría, F., 1 Oct 2025, In: Food Bioscience. 72, 107433.Research output: Contribution to journal › Article
2 Scopus citations
Activities
- 1 Oral presentation
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Congreso de la sociedad internacional de biología muscular
Castro Sepulveda, M. (Speaker)
2021Activity: Talk or presentation › Oral presentation