Projects per year
Personal profile
Research Interests
- Insulin sensitivity and lipotoxicity in obesity and associated metabolic alterations.
- Physical exercise and nutritional strategies for the prevention and treatment of metabolic diseases associated with obesity.
- Interaction between energy metabolism and circadian rhythms to optimize metabolic health.
- (Dys)mitochondrial function of skeletal muscle and metabolic health in elderly subjects.
- Regulation of substrate oxidation in health and in metabolic disorders associated with obesity.
Personal resume
Rodrigo Mancilla holds a PhD in Translational Medicine and Human Energy Metabolism from the School of Translational Nutrition and Metabolism Research (NUTRIM) at Maastricht University, the Netherlands. Following his doctoral degree, Dr. Rodrigo Mancilla was awarded by the European Foundation for the Study of Diabetes (EFSD) to continue his Postdoctoral research at Maastricht University, investigating the effects of physical exercise and nutritional supplementation with vitamin B3 on insulin sensitivity and mitochondrial function of skeletal muscle in elderly subjects. To conduct his research, Dr. Rodrigo Mancilla implements and applies gold-standard and non-invasive methodologies in humans with metabolic compromise, such as magnetic resonance spectroscopy (1H-MRS and 31P-MRS), euglycemic hyperinsulinemic clamp, muscle biopsies, and biopsies of other peripheral tissues. Currently, Dr. Rodrigo Mancilla is an Assistant Professor at Finis Terrae University, Faculty of Medicine, and his work is funded by national and international agencies such as ANID, Top Institute of Food and Nutrition (TiFN) Wageningen, EFSD, and NUTRIM.
Fingerprint
- 1 Similar Profiles
Projects
- 1 Active
-
FONDECYT de Iniciación 2024-¡Hit it hard! Effects of high intensity interval training on skeletal muscle insulin sensitivity in type 2 diabetes individuals.
Macilla Fuentes, R. (PI)
1/01/24 → 1/01/26
Project: Research › Applied research
-
Development of a 31P magnetic resonance spectroscopy technique to quantify NADH and NAD+ at 3 T
Mevenkamp, J., Bruls, Y. M. H., Mancilla, R., Grevendonk, L., Wildberger, J. E., Brouwers, K., Hesselink, M. K. C., Schrauwen, P., Hoeks, J., Houtkooper, R. H., Buitinga, M., de Graaf, R. A., Lindeboom, L. & Schrauwen-Hinderling, V. B., 1 Dec 2024, In: Nature Communications. 15, 1, 9159.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Invasive and noninvasive markers of human skeletal muscle mitochondrial function
Mancilla, R., Pava-Mejia, D., van Polanen, N., de Wit, V., Bergman, M., Grevendonk, L., Jorgensen, J., Kornips, E., Hoeks, J., Hesselink, M. K. C. & Schrauwen-Hinderling, V. B., 1 Jun 2023, In: Physiological Reports. 11, 12, e15734.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Skeletal muscle mitochondrial inertia is associated with carnitine acetyltransferase activity and physical function in humans
Mancilla, R. F., Lindeboom, L., Grevendonk, L., Hoeks, J., Koves, T. R., Muoio, D. M., Schrauwen, P., Schrauwen-Hinderling, V. & Hesselink, M. K. C., 10 Jan 2023, In: JCI Insight. 8, 1, e163855.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Exercise training elicits superior metabolic effects when performed in the afternoon compared to morning in metabolically compromised humans
Mancilla, R., Brouwers, B., Schrauwen-Hinderling, V. B., Hesselink, M. K. C., Hoeks, J. & Schrauwen, P., 1 Jan 2021, In: Physiological Reports. 8, 24, e14669.Research output: Contribution to journal › Article › peer-review
Open Access77 Scopus citations -
Gender differences in blood pressure and body composition in schoolchildren ascendants from Amerindian and European
Alvarez, C., Flores-Opazo, M., Mancilla, R., Martínez-Salazar, C., Mangiamarchi, P., Sade-Calles, F. & Ramírez-Campillo, R., 1 Jan 2021, In: Ethnicity and Health. 26, 6, p. 936-947 12 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations