Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties

Epsiba Lorena Marañon Romero; Ricardo Pascual Alanis Gómez; José Rafael Alanis-Gómez; Kevin José Martínez Arellano; Fabiola Hernández-Rosas; Rodrigo Velázquez Castillo

doi:10.1007/978-3-031-46936-7_14

Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties

Epsiba Lorena Marañon Romero, Ricardo Pascual Alanis Gómez, José Rafael Alanis-Gómez, Kevin José Martínez Arellano, Fabiola Hernández-Rosas, Rodrigo Velázquez Castillo

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Hydroxyapatite (HAp) is one of the most important in the family of calcium phosphates since it is an inorganic component of bone and it has been proven to be a biocompatible, osteoconductive, and osteoinductive material. However, it presents low antimicrobial activity making it susceptible to infections. This work aimed first to synthesize and characterize HAp nanofibers doped with Mg nanoparticles with a growth-oriented crystalline structure and second to evaluate their antimicrobial activity. For this, we synthesized HAp nanofibers by microwave-assisted hydrothermal method and carried out the structural characterization using the X-ray powder diffraction method. The morphological, topological, and microstructural characterization was performedwith scanning electron microscopy. Given the results, synthetic Mg-HAp nanofibers exhibited a hexagonal morphology and high purity and crystallinity. In addition, the nanofunctionality show of Mg-HAp exhibits good antimicrobial activity.

Original language	English
Title of host publication	46th Mexican Conference on Biomedical Engineering - Proceedings of CNIB 2023 - Volume 2
Subtitle of host publication	Biomechanics, Rehabilitation and Clinical Engineering
Editors	José de Jesús Agustín Flores Cuautle, Balam Benítez-Mata, Ricardo Antonio Salido-Ruiz, Hugo A. Vélez-Pérez, Gustavo Adolfo Alonso-Silverio, Guadalupe Dorantes-Méndez, Aldo Rodrigo Mejía-Rodríguez, Esmeralda Zúñiga-Aguilar, Edgar Del Hierro-Gutiérrez
Publisher	Springer Science and Business Media Deutschland GmbH
Pages	131-138
Number of pages	8
ISBN (Print)	9783031469350
DOIs	https://doi.org/10.1007/978-3-031-46936-7_14
State	Published - 1 Jan 2024
Event	46th Mexican Conference on Biomedical Engineering, CNIB 2023 - Villahermosa Tabasco, Mexico Duration: 2 Nov 2023 → 4 Nov 2023

Publication series

Name	IFMBE Proceedings
Volume	97
ISSN (Print)	1680-0737
ISSN (Electronic)	1433-9277

Conference

Conference	46th Mexican Conference on Biomedical Engineering, CNIB 2023
Country/Territory	Mexico
City	Villahermosa Tabasco
Period	2/11/23 → 4/11/23

Keywords

Antimicrobial Activity
Hydroxyapatite
Nanobiomaterial

Access to Document

10.1007/978-3-031-46936-7_14

Cite this

Romero, E. L. M., Gómez, R. P. A., Alanis-Gómez, J. R., Arellano, K. J. M., Hernández-Rosas, F., & Castillo, R. V. (2024). Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties. In J. D. J. A. Flores Cuautle, B. Benítez-Mata, R. A. Salido-Ruiz, H. A. Vélez-Pérez, G. A. Alonso-Silverio, G. Dorantes-Méndez, A. R. Mejía-Rodríguez, E. Zúñiga-Aguilar, & E. D. Hierro-Gutiérrez (Eds.), 46th Mexican Conference on Biomedical Engineering - Proceedings of CNIB 2023 - Volume 2: Biomechanics, Rehabilitation and Clinical Engineering (pp. 131-138). (IFMBE Proceedings; Vol. 97). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/978-3-031-46936-7_14

Romero, Epsiba Lorena Marañon ; Gómez, Ricardo Pascual Alanis ; Alanis-Gómez, José Rafael et al. / Combating Prosthetic Infections : Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties. 46th Mexican Conference on Biomedical Engineering - Proceedings of CNIB 2023 - Volume 2: Biomechanics, Rehabilitation and Clinical Engineering. editor / José de Jesús Agustín Flores Cuautle ; Balam Benítez-Mata ; Ricardo Antonio Salido-Ruiz ; Hugo A. Vélez-Pérez ; Gustavo Adolfo Alonso-Silverio ; Guadalupe Dorantes-Méndez ; Aldo Rodrigo Mejía-Rodríguez ; Esmeralda Zúñiga-Aguilar ; Edgar Del Hierro-Gutiérrez. Springer Science and Business Media Deutschland GmbH, 2024. pp. 131-138 (IFMBE Proceedings).

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title = "Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties",

abstract = "Hydroxyapatite (HAp) is one of the most important in the family of calcium phosphates since it is an inorganic component of bone and it has been proven to be a biocompatible, osteoconductive, and osteoinductive material. However, it presents low antimicrobial activity making it susceptible to infections. This work aimed first to synthesize and characterize HAp nanofibers doped with Mg nanoparticles with a growth-oriented crystalline structure and second to evaluate their antimicrobial activity. For this, we synthesized HAp nanofibers by microwave-assisted hydrothermal method and carried out the structural characterization using the X-ray powder diffraction method. The morphological, topological, and microstructural characterization was performedwith scanning electron microscopy. Given the results, synthetic Mg-HAp nanofibers exhibited a hexagonal morphology and high purity and crystallinity. In addition, the nanofunctionality show of Mg-HAp exhibits good antimicrobial activity.",

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editor = "{Flores Cuautle}, {Jos{\'e} de Jes{\'u}s Agust{\'i}n} and Balam Ben{\'i}tez-Mata and Salido-Ruiz, {Ricardo Antonio} and V{\'e}lez-P{\'e}rez, {Hugo A.} and Alonso-Silverio, {Gustavo Adolfo} and Guadalupe Dorantes-M{\'e}ndez and Mej{\'i}a-Rodr{\'i}guez, {Aldo Rodrigo} and Esmeralda Z{\'u}{\~n}iga-Aguilar and Hierro-Guti{\'e}rrez, {Edgar Del}",

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Romero, ELM, Gómez, RPA, Alanis-Gómez, JR, Arellano, KJM, Hernández-Rosas, F & Castillo, RV 2024, Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties. in JDJA Flores Cuautle, B Benítez-Mata, RA Salido-Ruiz, HA Vélez-Pérez, GA Alonso-Silverio, G Dorantes-Méndez, AR Mejía-Rodríguez, E Zúñiga-Aguilar & ED Hierro-Gutiérrez (eds), 46th Mexican Conference on Biomedical Engineering - Proceedings of CNIB 2023 - Volume 2: Biomechanics, Rehabilitation and Clinical Engineering. IFMBE Proceedings, vol. 97, Springer Science and Business Media Deutschland GmbH, pp. 131-138, 46th Mexican Conference on Biomedical Engineering, CNIB 2023, Villahermosa Tabasco, Mexico, 2/11/23. https://doi.org/10.1007/978-3-031-46936-7_14

Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties. / Romero, Epsiba Lorena Marañon; Gómez, Ricardo Pascual Alanis; Alanis-Gómez, José Rafael et al.
46th Mexican Conference on Biomedical Engineering - Proceedings of CNIB 2023 - Volume 2: Biomechanics, Rehabilitation and Clinical Engineering. ed. / José de Jesús Agustín Flores Cuautle; Balam Benítez-Mata; Ricardo Antonio Salido-Ruiz; Hugo A. Vélez-Pérez; Gustavo Adolfo Alonso-Silverio; Guadalupe Dorantes-Méndez; Aldo Rodrigo Mejía-Rodríguez; Esmeralda Zúñiga-Aguilar; Edgar Del Hierro-Gutiérrez. Springer Science and Business Media Deutschland GmbH, 2024. p. 131-138 (IFMBE Proceedings; Vol. 97).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - Combating Prosthetic Infections

T2 - 46th Mexican Conference on Biomedical Engineering, CNIB 2023

AU - Romero, Epsiba Lorena Marañon

AU - Gómez, Ricardo Pascual Alanis

AU - Alanis-Gómez, José Rafael

AU - Arellano, Kevin José Martínez

AU - Hernández-Rosas, Fabiola

AU - Castillo, Rodrigo Velázquez

N1 - Publisher Copyright: © The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.

PY - 2024/1/1

Y1 - 2024/1/1

N2 - Hydroxyapatite (HAp) is one of the most important in the family of calcium phosphates since it is an inorganic component of bone and it has been proven to be a biocompatible, osteoconductive, and osteoinductive material. However, it presents low antimicrobial activity making it susceptible to infections. This work aimed first to synthesize and characterize HAp nanofibers doped with Mg nanoparticles with a growth-oriented crystalline structure and second to evaluate their antimicrobial activity. For this, we synthesized HAp nanofibers by microwave-assisted hydrothermal method and carried out the structural characterization using the X-ray powder diffraction method. The morphological, topological, and microstructural characterization was performedwith scanning electron microscopy. Given the results, synthetic Mg-HAp nanofibers exhibited a hexagonal morphology and high purity and crystallinity. In addition, the nanofunctionality show of Mg-HAp exhibits good antimicrobial activity.

AB - Hydroxyapatite (HAp) is one of the most important in the family of calcium phosphates since it is an inorganic component of bone and it has been proven to be a biocompatible, osteoconductive, and osteoinductive material. However, it presents low antimicrobial activity making it susceptible to infections. This work aimed first to synthesize and characterize HAp nanofibers doped with Mg nanoparticles with a growth-oriented crystalline structure and second to evaluate their antimicrobial activity. For this, we synthesized HAp nanofibers by microwave-assisted hydrothermal method and carried out the structural characterization using the X-ray powder diffraction method. The morphological, topological, and microstructural characterization was performedwith scanning electron microscopy. Given the results, synthetic Mg-HAp nanofibers exhibited a hexagonal morphology and high purity and crystallinity. In addition, the nanofunctionality show of Mg-HAp exhibits good antimicrobial activity.

KW - Antimicrobial Activity

KW - Hydroxyapatite

KW - Nanobiomaterial

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SN - 9783031469350

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BT - 46th Mexican Conference on Biomedical Engineering - Proceedings of CNIB 2023 - Volume 2

A2 - Flores Cuautle, José de Jesús Agustín

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A2 - Salido-Ruiz, Ricardo Antonio

A2 - Vélez-Pérez, Hugo A.

A2 - Alonso-Silverio, Gustavo Adolfo

A2 - Dorantes-Méndez, Guadalupe

A2 - Mejía-Rodríguez, Aldo Rodrigo

A2 - Zúñiga-Aguilar, Esmeralda

A2 - Hierro-Gutiérrez, Edgar Del

PB - Springer Science and Business Media Deutschland GmbH

Y2 - 2 November 2023 through 4 November 2023

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Romero ELM, Gómez RPA, Alanis-Gómez JR, Arellano KJM, Hernández-Rosas F, Castillo RV. Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties. In Flores Cuautle JDJA, Benítez-Mata B, Salido-Ruiz RA, Vélez-Pérez HA, Alonso-Silverio GA, Dorantes-Méndez G, Mejía-Rodríguez AR, Zúñiga-Aguilar E, Hierro-Gutiérrez ED, editors, 46th Mexican Conference on Biomedical Engineering - Proceedings of CNIB 2023 - Volume 2: Biomechanics, Rehabilitation and Clinical Engineering. Springer Science and Business Media Deutschland GmbH. 2024. p. 131-138. (IFMBE Proceedings). doi: 10.1007/978-3-031-46936-7_14

Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties

Abstract

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Combating Prosthetic Infections: Synthesis, Characterization, and Evaluation of Magnesium-Doped Hydroxyapatite Nanofibers with Antibacterial Properties

Abstract

Publication series

Conference

Keywords

Access to Document

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Cabina de Seguridad Biológica Clase II Tipo A2

Reactor de microondas Monowave 450 Anton Paar

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