Sleep regulation by exogenous and endogenous cannabinoids

Gerardo Viana-Torre, Sergio Machado, Henning Budde, Claudio Imperatori, Alberto Souza Sá Filho, Ali Yadollahpour, Fabio García-García, Tetsuya Yamamoto, Pablo Torterolo, Eric Murillo-Rodríguez

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

The sleep-wake cycle is a neurobiological phenomenon driven by the complex interaction of different neuroanatomical, neurochemical, and genetic networks. In addition, sleep is also under the strict influence of circadian and homeostatic factors modulating its appearance ∼24h. Furthermore, sleep-wake cycle is also under the effects of exogenous and endogenous compounds. In this chapter, we provide the state of the art in the field of the sleep control by chemicals derived from Cannabis sativa (cannabinoids) and the endocannabinoid system.

Original languageEnglish
Title of host publicationMedicinal Usage of Cannabis and Cannabinoids
PublisherElsevier
Pages385-392
Number of pages8
ISBN (Electronic)9780323900362
ISBN (Print)9780323915786
DOIs
StatePublished - 1 Jan 2023

Keywords

  • Anandamide
  • Cannabis sativa
  • Fatty acid amide hydrolase
  • Slow wave sleep
  • Wakefulness

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