TY - GEN
T1 - Biomedical Potential of the Methanolic Leaf Extract of Verbesina persicifolia
T2 - Joint 20th Nordic-Baltic Conference on Biomedical Engineering and 24th Polish Conference on Biocybernetics and Biomedical Engineering, NBC 2025 and PCBBE 2025
AU - López-Rosas, Carlos Alberto
AU - Han, Seojin
AU - Vélez, Margarita V.Saavedra
AU - Gómez, José Rafael Alanis
AU - Hernández-Rosas, Fabiola
N1 - Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.
PY - 2025/1/1
Y1 - 2025/1/1
N2 - Extracts from the leaves of plants of the genus Verbesina have shown promising biomedical potential, especially for their antimicrobial and anti-inflammatory properties and their application in wound healing. In this study, we analyzed the biological properties of the methanolic extract of Verbesina persicifolia using the minimum inhibitory concentration (MIC) assay to determine its antimicrobial activity against various pathogenic bacteria. In addition, cell viability was evaluated using the Alamar Blue assay to determine the effect of plant extracts on bacterial viability and the cytotoxicity of the extracts in murine fibroblasts in culture. The results demonstrated significant antimicrobial activity, making the extract a potential candidate for the development of new antimicrobial agents. Furthermore, the non-toxic effects on fibroblasts highlight its potential to promote wound healing, suggesting that Verbesina persicifolia could serve as a natural alternative for therapeutic applications in wound management.
AB - Extracts from the leaves of plants of the genus Verbesina have shown promising biomedical potential, especially for their antimicrobial and anti-inflammatory properties and their application in wound healing. In this study, we analyzed the biological properties of the methanolic extract of Verbesina persicifolia using the minimum inhibitory concentration (MIC) assay to determine its antimicrobial activity against various pathogenic bacteria. In addition, cell viability was evaluated using the Alamar Blue assay to determine the effect of plant extracts on bacterial viability and the cytotoxicity of the extracts in murine fibroblasts in culture. The results demonstrated significant antimicrobial activity, making the extract a potential candidate for the development of new antimicrobial agents. Furthermore, the non-toxic effects on fibroblasts highlight its potential to promote wound healing, suggesting that Verbesina persicifolia could serve as a natural alternative for therapeutic applications in wound management.
KW - antimicrobial properties
KW - cytotoxicity
KW - medicinal plants
KW - methanolic extract
KW - Verbesina persicifolia
UR - https://www.scopus.com/pages/publications/105010204227
U2 - 10.1007/978-3-031-96538-8_24
DO - 10.1007/978-3-031-96538-8_24
M3 - Contribución a la conferencia
AN - SCOPUS:105010204227
SN - 9783031965371
T3 - IFMBE Proceedings
SP - 286
EP - 293
BT - Joint 20th Nordic-Baltic Conference on Biomedical Engineering and 24th Polish Conference on Biocybernetics and Biomedical Engineering - Joint Proceedings of NBC 2025 and PCBBE 2025
A2 - Ladyzynski, Piotr
A2 - Pijanowska, Dorota G.
A2 - Liebert, Adam
PB - Springer Science and Business Media Deutschland GmbH
Y2 - 16 June 2025 through 18 June 2025
ER -