Lysosomal and mitochondrial liaisons in Niemann-Pick disease

Keyphrases

• Mitochondrium 100%
• Mitochondria 100%
• Niemann-Pick Disease 100%
• Cholesterol 66%
• Lysosome 66%
• Lysosomal Storage Disease 66%
• Specific Lipids 66%
• Membrane Contact Sites 66%
• Lipid Species 66%
• Mitochondrial Dysfunction 33%
• NP-C 33%
• Niemann-Pick C1-like 1 (NPC1L1) 33%
• Disease Progression 33%
• Endoplasmic Reticulum 33%
• Antioxidant System 33%
• Lysosomal Function 33%
• Acid Sphingomyelinase 33%
• Biochemical Features 33%
• Sphingolipids 33%
• Intracellular Trafficking 33%
• Endolysosome 33%
• Lysosomal Homeostasis 33%
• Close Proximity 33%
• Secondary Accumulation 33%
• Functional Defects 33%
• Functional Regulation 33%
• Loss Function 33%
• Niemann-Pick Type C 33%
• Niemann-Pick Type 33%
• Sterol Lipids 33%

Biochemistry, Genetics and Molecular Biology

• Lipid 100%
• Niemann-Pick Disease 100%
• Mitochondrion 75%
• Lysosome 50%
• NPC1 25%
• Acid Sphingomyelinase 25%
• Sterol 25%
• Sphingomyelin Phosphodiesterase 25%
• Homeostasis 25%
• Intracellular Trafficking 25%
• Mitochondrial Disorder 25%
• Sphingolipid 25%

Neuroscience

• Mitochondrion 100%
• Pick's Disease 100%
• Lysosome 66%
• Antioxidant 33%
• Sterol 33%
• Intracellular Trafficking 33%
• Sphingolipid 33%
• Sphingomyelin Phosphodiesterase 33%
• Endoplasmic Reticulum 33%