TY - JOUR
T1 - Multi-response optimal hot pressurized liquid recovery of extractable polyphenols from leaves of maqui (Aristotelia chilensis [Mol.] Stuntz)
AU - Rivera-Tovar, Pamela Raquel
AU - Torres, María Dolores
AU - Camilo, Conrado
AU - Mariotti-Celis, María Salomé
AU - Domínguez, Herminia
AU - Pérez-Correa, José Ricardo
N1 - Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/9/30
Y1 - 2021/9/30
N2 - Multi-response optimization of hot pressurized liquid extraction (HPLE) was applied for the first time to obtain maqui (Aristotelia chilensis [Mol.] Stuntz) leaf extracts. The total polyphenol content (TPC), the antioxidant capacity (AC) as well as the total polyphenol purity of the maqui leaf extracts were accurately predicted (RSD < 8%) at the evaluated extraction scales. The optimum HPLE conditions that prioritized TPC and AC equally (OPT1) recovered ~3 times more TPC (205.14 mg GAE/g leaves) than maqui leaf extracts obtained by maceration, while the extract that prioritized purity over TPC and AC presented the highest purity (36.29%) and an EC50 ~3 times lower than currently reported values. It was found by multi-response optimization that maqui leaves and HPLE are among the best natural sources and extraction techniques, respectively, to recover protocatechuic acid, quercetin, and catechin.
AB - Multi-response optimization of hot pressurized liquid extraction (HPLE) was applied for the first time to obtain maqui (Aristotelia chilensis [Mol.] Stuntz) leaf extracts. The total polyphenol content (TPC), the antioxidant capacity (AC) as well as the total polyphenol purity of the maqui leaf extracts were accurately predicted (RSD < 8%) at the evaluated extraction scales. The optimum HPLE conditions that prioritized TPC and AC equally (OPT1) recovered ~3 times more TPC (205.14 mg GAE/g leaves) than maqui leaf extracts obtained by maceration, while the extract that prioritized purity over TPC and AC presented the highest purity (36.29%) and an EC50 ~3 times lower than currently reported values. It was found by multi-response optimization that maqui leaves and HPLE are among the best natural sources and extraction techniques, respectively, to recover protocatechuic acid, quercetin, and catechin.
KW - Accelerated solvent extraction (ASE)
KW - Chlorogenic acid (PubChem CID1794427)
KW - Desirability function (DF)
KW - Extract's polyphenol purity
KW - Gallic acid (PubChem CID370)
KW - Number of cycles
KW - Polyphenol extraction yield
KW - Response surface methodology (RSM)
KW - catechin (PubChem CID9064)
KW - cinnamic acid (PubChem CID444539)
KW - coumaric acid (PubChem CID637542)
KW - hydroxytyrosol (PubChem CID82755)
KW - kaempferol (PubChem CID5280863)
KW - protocatechuic acid (PubChem CID72)
KW - quercetin (PubChem CID5280343)
KW - resveratrol (PubChem CID445154)
UR - https://www.scopus.com/pages/publications/85105462245
U2 - 10.1016/j.foodchem.2021.129729
DO - 10.1016/j.foodchem.2021.129729
M3 - Artículo
C2 - 33984739
AN - SCOPUS:85105462245
SN - 0308-8146
VL - 357
JO - Food Chemistry
JF - Food Chemistry
M1 - 129729
ER -