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Biomedical Potential of the Methanolic Leaf Extract of Verbesina persicifolia: Antimicrobial Properties and Applications in Wound Healing

  • Carlos Alberto López-Rosas
    ,
  • Seojin Han
    ,
  • Margarita V.Saavedra Vélez
    ,
  • José Rafael Alanis Gómez
    ,
  • Fabiola Hernández-Rosas(corresponding author)
*Corresponding author for this work
Research Output:
Chapter in Book/Report/Conference proceeding
Conference contribution

Publication Information

Output type

Research Output:
Chapter in Book/Report/Conference proceeding
Conference contribution

Original language

English

Article number

24

Pages from-to (Number of pages)

Pages 286-293 (8 pages)

Publication milestones

  • Published - 01/01/2025

Publication status

Published - 01/01/2025

Edition

20

Volume

131

Publisher

Springer Science and Business Media Deutschland GmbH

Publication series

  • Publication series name: IFMBE Proceedings
    ISSN (Print): 1680-0737
    ISSN (Electronic): 1433-9277
    Volume: 131
9783031965371

ISBN (Electronic)

978-3-031-96538-8

Publication IDs

  • Scopus: 105010204227

Host publication title

Joint 20th Nordic-Baltic Conference on Biomedical Engineering and 24th Polish Conference on Biocybernetics and Biomedical Engineering - Joint Proceedings of NBC 2025 and PCBBE 2025

Host publication editors

  • Piotr Ladyzynski
  • Dorota G. Pijanowska
  • Adam Liebert

Abstract

Extracts from the leaves of plants of the genus Verbesina have shown promising biomedical potential, especially for their antimicrobial and anti-inflammatory properties and their application in wound healing. In this study, we analyzed the biological properties of the methanolic extract of Verbesina persicifolia using the minimum inhibitory concentration (MIC) assay to determine its antimicrobial activity against various pathogenic bacteria. In addition, cell viability was evaluated using the Alamar Blue assay to determine the effect of plant extracts on bacterial viability and the cytotoxicity of the extracts in murine fibroblasts in culture. The results demonstrated significant antimicrobial activity, making the extract a potential candidate for the development of new antimicrobial agents. Furthermore, the non-toxic effects on fibroblasts highlight its potential to promote wound healing, suggesting that Verbesina persicifolia could serve as a natural alternative for therapeutic applications in wound management.