Skip to search boxSkip to navigationSkip to main content

Biophysical evidence of lipid and carbohydrate binding activities of shrimp high density lipoprotein/β glucan binding protein

  • Claudia L. Vargas-Requenaa(Author)
    ,
  • Alejandra Hernández-Santoyoa(Author)
    ,
  • Gloria Yepiz-Plascenciaa(Author)
    ,
  • Francisco Vargas-Alboresa(Author)
    ,
  • Inocencio Higuera-Ciaparaa(Author)
    ,
  • Adela Rodríguez-Romeroa(Author)
  • aCtr. de Invest. en Aliment. y Desar.
Research Output: Contribution to journal Article Peer-review

Publication Information

Output type

Research Output: Contribution to journal Article Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 337-344 (8 pages)

Journal (Volume, Issue Number)

Protein and Peptide Letters (Volume 9, Issue 4)

Publication milestones

  • Published - 30/07/2002

Publication status

Published - 30/07/2002

ISSN

0929-8665

External Publication IDs

  • Scopus: 0036069413
  • PubMed: 12144511

Abstract

Crustacean High Density Lipoprotein/β-Glucan Binding Protein (HDL/BGBP) has been studied due to its role in nutrition and immune response via activation of the defense cells (hemocytes) upon binding 1,3-D-β-glucan carbohydrates. In this study, HDL/BGBP was found to be composed mainly of beta sheets, as determined by circular dichroism. Lipoprotein aggregation resulted when HDL/BGBP interacted with phospolipid vesicles, laminaribiose (1,3-β-glucan disaccharide) or heparin. HDL/BGBP has similar dissociation constants for laminaribiose (Kd=22 mM) or heparin (Kd=46 mM) as determined by 90° light scattering.

Access to documents

Publication metrics

Metrics

SciVal
FWCI
0.18