Infección del tracto urinario por Rodentibacter pneumotropicus (Pasteurella Pneumotropica) en un paciente inmunocompetente: Infección urinaria por Rodentibacter pneumotropicus en paciente inmunocompetente

Título original: Rare Urinary Tract Infection by Rodentibacter pneumotropicus (formerly, Pasteurella pneumotropica) in an Immunocompetent Patient

Elena Soto-Vega
,
Elizabeth Bello-Rossette
,
María Del Carmen Cabrera-Martínez
,
José Carlos Arroyo Kuribreña

Escuela de Medicina
,
Universidad de la Salud del Estado de Puebla
,
Morehouse School of Medicine

Research Output:

Contribución a una revista

Artículo

Revisión por expertos

Publication Information

Tipo de resultado

Research Output:

Contribución a una revista

Artículo

Revisión por expertos

Idioma original

Inglés

Páginas desde-hasta (Número de páginas)

Páginas e947344

Revista (Volumen, Número de Edición)

The American journal of case reports (Volumen 26)

Hitos de publicación

Publicada - 13/06/2025

Estado de publicación

Publicada - 13/06/2025

ISSN

1941-5923

Publication IDs

PubMed: 40512687

Abstract

BACKGROUND Pasteurella pneumotropica has been reclassified as Rodentibacter pneumotropicus after advancements in genetic and phenotypic analyses revealed genetic diversity and phylogenetic distinctions within the pneumotropica complex. This reorganization resolved issues of misclassification and provided a clearer framework for understanding the epidemiology and clinical relevance of these organisms. R. pneumotropicus is a gram-negative bacillus commonly found in the respiratory tracts of mammals, particularly rodents. However, it rarely infects humans. This case is notable for presenting a urinary tract infection caused by R. pneumotropicus in an immunocompetent patient, a rare manifestation highlighting the need to consider less-common pathogens in daily clinical practice to choose the correct treatments. CASE REPORT This case describes a 37-year-old immunocompetent man who initially presented to a hospital in Mexico with gastrointestinal symptoms and later developed urinary issues following a ureteroscopy for a proximal ureteral stone. Despite initial treatment with meropenem and paracetamol, the patient had persistent fever and leukocytosis. According to the available material at the hospital, a urine culture was done subsequently and it revealed R. pneumotropicus, formerly known as Pasteurella pneumotropica, which was sensitive to fluoroquinolones. The patient underwent transurethral resection of the prostate and was treated with ciprofloxacin, leading to successful symptom resolution. CONCLUSIONS This case highlights the rarity of urinary tract infections caused by R. pneumotropicus in immunocompetent individuals. These findings underscore the importance of considering uncommon microorganisms in differential diagnoses and ensuring precise identification and sensitivity testing to guide effective treatment. Also, it provides evidence supporting the ability of R. pneumotropicus to infect immunocompetent individuals, raising several questions related to its infection mechanisms.